Feb 15, 2023

S4Llite – One Step Ahead into the Future

S4Llite – One Step Ahead into the Future 

ZMT has natively implemented the computational life science platform Sim4Life in the cloud. Thanks to innovative and powerful new technology, the web version delivers the same performance that the Sim4Life desktop version can achieve on the most powerful desktop machine, but with instant sharing capabilities and without the overhead or the need for high-end hardware.

Sim4Life is the premier simulation platform used by academic and industry leaders in biomedical research and development for the most complex and advanced multiphysics simulations in complex environments like the human body.

Until today, a powerful desktop computer with advanced graphics cards was required to deal with the complexity of the Sim4Life platform. However, ZMT has taken a major leap into the future by leveraging the highly innovative o2S2PARC technology developed by the IT’IS Foundation under the NIH SPARC program to create a new cloud-based version of the powerful Sim4Life platform on the web: S4L.

Today, we released S4Llite, the student version of the soon-to-be released full version S4L

S4Llite in action: Watch the movie here.

S4Llite allows students to easily access, run, and share simulations in the cloud from any web browser. It offers the same features and performance as the Sim4Life desktop version but is more flexible, maintenance-free, and even easier to use. Most importantly, it does not require powerful in-house computational resources, as it relies on scalable cloud-computing infrastructure. S4Llite replaces the desktop version Sim4Life Light and is available free of charge for students.

Students from registered universities can access S4Llite through a free and easy-to-set-up online account. Existing users of the desktop version Sim4Life Light can smoothly migrate to the S4Llite version by uploading their projects to the online platform.

The full version of S4L, to be released in the spring, will provide unrestricted performance for the most complex modeling and simulation tasks in the cloud, along with full integration in the o2S2PARC platform, with its many additional tools and functionalities. Scientists will be able to integrate their S4L modeling with any other computational tools, or develop their own pipelines and applications and share them with the scientific community.

ZMT remains committed in supporting learning, education, and scientific research. Register here for S4Llite.

The Sim4Life Team


Example showing coupling of electromagnetics and neuronal dynamics simulations in S4Llite to investigate neurostimulation related quantities in the context of electroceuticals and bioelectronics medicine: shown is an electrode pair for electrical stimulation to initiate a neuroelectric response in the nerve trajectories located in the Virtual Population Yoon-sun V3.1 arm model.


Simulation showing a patch antenna array operating at mmWave frequency (28 GHz) in S4Llite to investigate the beam-steering capability of the antenna and the power density of the incident electromagnetic field on the cheek of the Yoon-sun V3.1 full body model.


S4Llite provides powerful ways to share entire projects and studies with classmates, teachers and educational groups, allowing students to easily collaborate and learn together.

Dashboard Tutorials

The Dashboard in S4Llite allows for quick and easy access and intuitive organization of users’ projects. The platform provides a rich and ever-growing set of entry-level as well as advanced and complex tutorials.




Oct 5, 2021



Sim4Life V6.2.2 Maintenance Release

The Sim4Life Team announced the release of Sim4Life V6.2.2, an updated version of Sim4Life V6.2.1.


Sep 7, 2021



2021 MIMAS Implant Safety Workshop

ZMT is the co-organizer of the virtual 2021 MIMAS Implant Safety Workshop on September 15–16, 2021


May 25, 2021



FDA Extends MDDT Qualification to IMAnalytics V3.0 and MRIxViP V2.1

FDA Qualification of the ZMT & IT’IS MDDT toolset IMAnalytics with MRIxViP1.5T/3.0T and BCLib now also includes passive implants (ASTM F2182-19ε2) and Region-of-Interest Field Extraction for ISO 10974 Tier 2.


May 14, 2021



Sim4Life at the 2021 ISMRM & SMRT Annual Meeting & Exhibition

Sim4Life will be showcased by several users at the Virtual ISMRM 2021, don’t miss their contributions!


May 11, 2021



Sim4Life V6.2.1 Maintenance Release

The Sim4Life Team announced the release of Sim4Life V6.2.1, an updated version of Sim4Life V6.2.


Mar 16, 2021



IT’IS Releases Four New Mouse Models Segmented From Whole-Body MR Images

The IT’IS Foundation has released four new mouse models segmented from magnetic resonance imaging data. All four models are optimized for Sim4Life.


Feb 23, 2021



Sim4Life Release V6.2

ZMT has deployed a new release of its Sim4Life platform. V6.2 not only comes with a smoother look and feel and a better user experience but also with important new features, refinements, and bug fixes. 

Page 4 of 24