Major Release: Sim4Life V2.0

ZMT Zurich Med Tech is pleased to announce the release of Sim4Life V2.0, a major update that takes the first comprehensive simulation platform to combine high-fidelity computable human phantoms with powerful physics solvers and advanced tissue models to new heights. This release delivers significant new improvements and capabilities to directly analyze biological real-world phenomena and complex technical devices in a validated biological and anatomical environment.

The advanced ViP V3.0 anatomical phantoms and the new solvers and tools greatly extend the range of tailored applications for Sim4Life to include neuroprosthetics, neurostimulation, therapeutic ultrasound treatment, focused ultrasound ablation, applicator development, acoustic exposure, vascular implants, biofluidics, and respiratory flow.

We also continued our efforts to improve our quality and traceability assurance (models), verification (code), and validation (applications) procedures. All current and future models are and will be assigned a unique digital object identifier (DOI), ensuring the availability of the model at any time. We are committed to providing high quality verification and validation documents for internal QA and regulatory submissions. 

V2.0 widens its lead as the most comprehensive solution for MRI equipment, pulse sequence and imaging optimization and for compliance and safety assessments of implants with significant enhancements to the existing MRI modeling capabilities.

Key new features of Sim4Life V2.0 include:

• Fully posable, high-fidelity, 3D computable Virtual Population anatomical models.
• A subgrid EM-FDTD engine that locally resolves the model at extreme detail with reduced simulation times and computationally supports its accuracy. Like our main FDTD implementation, the subgrid engine uses GPUs to achieve even faster turnaround times.
• A new neuronal dynamics module that embeds realistic neuronal dynamics simulations into the simulation flows (coupled EM-neuronal dynamics). Additional solvers address acoustics and biofluidics.
• Framework enhancements such as the concurrent handling of meshes and NURBS, an entirely new and user friendly Python API, and a Workbench for complex analysis and visualization pipelines.
• Embedded and streamlined modeling capabilities ranging from medical image data segmentation, anatomical and CAD model import, discretization and simulation to visualization and analysis in the most versatile and efficient simulation environment.

The complete list of improvements and fixes is included in the Release Notes.

If you are interested in experiencing the power and elegance of Sim4Life V2.0, or require further information, please feel free to email us at s4l-sales@zmt.swiss or call us at +41 44 245 9765. For our existing customers, all pertinent information regarding the Software Installer Download and updated licenses will be individually provided.

At ZMT Zurich Med Tech, we are dedicated to empowering our customers to reach new heights of productivity and scientific achievement by providing the most innovative software solutions, testing equipment, and support.

s4l-sales@zmt.swiss

Neuronal stimulation in human spine: simulation of nerve stimulus (dendrite) using the new S4L neuronal dynamics solver with smoothly embedded NEURON solver.

Endoscopy via biotelemetry in the human intestine: the use of the novel S4L EM-FDTD subgrid engine & GPU for refining the wireless capsule in a whole body model allowed a reduction of computation time from half a week to one hour.

Focused ultrasound ablation: optimization of focusing area (considering bones, skull) in the human brain with a multi-element phased array transducer using the novel S4L acoustic solver.