Lots of Interest in Sim4Life Workshop @ Neuroscience 2018

On November 5, 2018, about 60 neuroscientists and representatives of the medical device industry convened at the Sim4Life Workshop at Neuroscience 2018 in San Diego, USA. The event was hosted by Michael Oberle and Habib Bousleiman of ZMT. Distinguished speakers shared their experience and their vision on how the Sim4Life platform can be employed to master a myriad of challenges in bioelectronic medicine.

 “A Computational Framework for the Design and Optimization of Neurotechnologies to Restore Voluntary Motor Control after Paralysis”, was the title of the outstanding keynote lecture given by Marco Capogrosso from the University of Fribourg, Switzerland. He showed how computational modeling and simulations have helped to establish experimental proof of concepts in pre-clinical studies and how to translate this experience into clinical studies. Marco also highlighted how ZMT’s simulation platform Sim4Life and the high-resolution personalized anatomical model generation functionality were key to address patient specific motor deficits and guide the design and positioning of the stimulating electrodes in several of his studies. His latest results were released earlier this month in a widely-discussed publication that was also reported in a news item by the IT’IS Foundation.

Théo Lemaire from the EPFL Lausanne, Switzerland, provided insights into his research on Low Intensity Focused Ultrasound Stimulation (LIFUS) with a particular focus on the derivation of the computationally effective SONIC model for improved predictions on interactions between neurons and LIFUS. He demonstrated how Sim4Life helped his team to perform multiscale modeling of acoustic wave propagation within the human anatomy in order to predict the resulting electrophysiological neuron response. The unique capabilities of Sim4Life enabled him to formulate testable mechanistic hypotheses and guide the experimental design. 

Silvia Farcito and Antonino Mario Cassará (IT’IS Foundation, Switzerland) introduced the first next generation neuro-functionalized computational anatomical human model Yoon-sun V4.0, and and gave an update on the latest developments and applications of the upcoming version Sim4Life V4.4.  

Esra Neufeld (IT’IS Foundation, Switzerland) outlined the progress and outlook of the o2S2PARC project, one of the three data resource center COREs of the NIH-funded SPARC initiative. The ongoing project aims to provide the scientific community with an open-access online simulation platform for the modeling of nerve-organ interactions within complex physiological environments and for the integration of all computational models established within the SPARC initiative.

Habib Bousleiman concluded the evening with an outlook on selected features of upcoming Sim4Life releases that will enable researchers and engineers to further explore the frontiers in neuroscience. 

All presentations were met with great interest. The attendees enjoyed a light dinner buffet during the event, which was closed with a networking aperitif where participants had the chance to discuss remaining questions and share their experiences with each other.

Once again, many thanks to everyone who contributed to the success of this year's event and don't miss the Sim4Life Workshop @ Neuroscience 2019, which will be held in October 2019 in Chicago, USA!


Dr. Marco Capogrosso, during his keynote presentation


Théo Lemaire from the EPFL Lausanne, delivering his presentation


Dr. Antonino Mario Cassará, giving updates on the latest developments in Sim4Life


Z43 team in front of the ZMT booth 





Sim4Life is Ready for Yoon-sun V4.0

Yoon-sun V4.0 is the first neuro-functionalized computational anatomical model to support novel applications in neurostimulation and exposure/ device safety assessment.





o2S2PARC Project Continues Full-Speed into Its Second Year

The IT’IS o2S2PARC team has been awarded a second year of funding by the U.S. National Institutes of Health! In year 2, the focus will be on usability, simulators, and onboarding of first users.





ZMT Sim4Life Workshop at Neuroscience 2018: Agenda & Registration

With Neuroscience 2018, the Society for Neuroscience Annual Meeting, in San Diego, USA, only being a few weeks away, we are excited to announce that we will hold our second SfN Sim4Life Workshop on Monday, November 5, 2018, from 6:30pm – 9:00pm.






Sim4Life Workshop at Neuroscience 2018

With Neuroscience 2018, the Society for Neuroscience Annual Meeting, in San Diego, USA, only being a few weeks away, we are excited to announce that we will hold our second SfN Sim4Life Workshop on Monday, November 5, 2018, from 6:30pm – 9:30pm.






Sim4Life V4.2 Release

The Sim4Life Team is pleased to announce the release of Sim4Life V4.2, an updated version of Sim4Life V4.0.1.





Sim4Life light: Explore the World of Complex Physiological Modelling and Simulations – for Free!

ZMT announces the release of Sim4Life light, a new edition specifically designed for students who can now use our cutting-edge computational life science platform for their research at no cost.





New Computational Phantom Yoon-sun: Important ViP Extension in Unmatched Segmentation Quality

The first non-European computational anatomical model and member of the Virtual Population (ViP), Yoon-sun cV3.1, has been released. The new phantom includes detailed organs, vessel trees, and peripheral nerves.

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