Feb 15, 2023

S4Llite – One Step Ahead into the Future

S4Llite – One Step Ahead into the Future 

ZMT has natively implemented the computational life science platform Sim4Life in the cloud. Thanks to innovative and powerful new technology, the web version delivers the same performance that the Sim4Life desktop version can achieve on the most powerful desktop machine, but with instant sharing capabilities and without the overhead or the need for high-end hardware.

Sim4Life is the premier simulation platform used by academic and industry leaders in biomedical research and development for the most complex and advanced multiphysics simulations in complex environments like the human body.

Until today, a powerful desktop computer with advanced graphics cards was required to deal with the complexity of the Sim4Life platform. However, ZMT has taken a major leap into the future by leveraging the highly innovative o2S2PARC technology developed by the IT’IS Foundation under the NIH SPARC program to create a new cloud-based version of the powerful Sim4Life platform on the web: S4L.

Today, we released S4Llite, the student version of the soon-to-be released full version S4L

S4Llite in action: Watch the movie here.

S4Llite allows students to easily access, run, and share simulations in the cloud from any web browser. It offers the same features and performance as the Sim4Life desktop version but is more flexible, maintenance-free, and even easier to use. Most importantly, it does not require powerful in-house computational resources, as it relies on scalable cloud-computing infrastructure. S4Llite replaces the desktop version Sim4Life Light and is available free of charge for students.

Students from registered universities can access S4Llite through a free and easy-to-set-up online account. Existing users of the desktop version Sim4Life Light can smoothly migrate to the S4Llite version by uploading their projects to the online platform.

The full version of S4L, to be released in the spring, will provide unrestricted performance for the most complex modeling and simulation tasks in the cloud, along with full integration in the o2S2PARC platform, with its many additional tools and functionalities. Scientists will be able to integrate their S4L modeling with any other computational tools, or develop their own pipelines and applications and share them with the scientific community.

ZMT remains committed in supporting learning, education, and scientific research. Register here for S4Llite.

The Sim4Life Team


Example showing coupling of electromagnetics and neuronal dynamics simulations in S4Llite to investigate neurostimulation related quantities in the context of electroceuticals and bioelectronics medicine: shown is an electrode pair for electrical stimulation to initiate a neuroelectric response in the nerve trajectories located in the Virtual Population Yoon-sun V3.1 arm model.


Simulation showing a patch antenna array operating at mmWave frequency (28 GHz) in S4Llite to investigate the beam-steering capability of the antenna and the power density of the incident electromagnetic field on the cheek of the Yoon-sun V3.1 full body model.


S4Llite provides powerful ways to share entire projects and studies with classmates, teachers and educational groups, allowing students to easily collaborate and learn together.

Dashboard Tutorials

The Dashboard in S4Llite allows for quick and easy access and intuitive organization of users’ projects. The platform provides a rich and ever-growing set of entry-level as well as advanced and complex tutorials.




Nov 5, 2018



Sim4Life is Ready for Yoon-sun V4.0

Yoon-sun V4.0 is the first neuro-functionalized computational anatomical model to support novel applications in neurostimulation and exposure/ device safety assessment.


Oct 23, 2018



o2S2PARC Project Continues Full-Speed into Its Second Year

The IT’IS o2S2PARC team has been awarded a second year of funding by the U.S. National Institutes of Health! In year 2, the focus will be on usability, simulators, and onboarding of first users.


Oct 16, 2018



ZMT Sim4Life Workshop at Neuroscience 2018: Agenda & Registration

With Neuroscience 2018, the Society for Neuroscience Annual Meeting, in San Diego, USA, only being a few weeks away, we are excited to announce that we will hold our second SfN Sim4Life Workshop on Monday, November 5, 2018, from 6:30pm – 9:00pm.



Oct 5, 2018



Sim4Life Workshop at Neuroscience 2018

With Neuroscience 2018, the Society for Neuroscience Annual Meeting, in San Diego, USA, only being a few weeks away, we are excited to announce that we will hold our second SfN Sim4Life Workshop on Monday, November 5, 2018, from 6:30pm – 9:30pm.



Sep 27, 2018



Sim4Life V4.2 Release

The Sim4Life Team is pleased to announce the release of Sim4Life V4.2, an updated version of Sim4Life V4.0.1.


Sep 18, 2018



Sim4Life light: Explore the World of Complex Physiological Modelling and Simulations – for Free!

ZMT announces the release of Sim4Life light, a new edition specifically designed for students who can now use our cutting-edge computational life science platform for their research at no cost.


Jul 31, 2018



New Computational Phantom Yoon-sun: Important ViP Extension in Unmatched Segmentation Quality

The first non-European computational anatomical model and member of the Virtual Population (ViP), Yoon-sun cV3.1, has been released. The new phantom includes detailed organs, vessel trees, and peripheral nerves.

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