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Jun 17, 2025
Sim4Life

Advanced Computational Life Science Applications at CNS*2025

We are excited to announce that we will present a packed program at the Annual Meeting of the Organization for Computational Neuroscience (CNS*2025), to be held July 5 – 9, 2025, in Florence, Italy – together with our Z43 partner IT'IS Foundation.

Kicking things off, we will host a half-day tutorial that provides participants with a hands-on introduction to our latest cloud-native platforms, o2S2PARC and Sim4Life.web:

 

Saturday July 5, 2025, 09:00 AM – 12:00 PM CEST, Room 5

Half-Day Tutorial “Computational Life Science in the Cloud: Neurostimulation and Bioelectronic Medicine with o²S²PARC & Sim4Life” (register here!)

09:00 AM

Intro to Image- & Cloud-Based Modeling for Real-World Applications

09:15 AM

Getting Started with o²S²PARC & Sim4Life.web

09:45 AM

Electromagnetic-Neuro Interactions Across Spatio-Temporal Scales (Brain, Spine, Peripheral Nervous System)

10:25 AM

Coffee Break

10:45 AM

Hands-On Exercises:

  • Modeling the Brain Response to Non-Invasive Brain Stimulation
  • Modeling Vagus nerve Stimulation for Cardiac Health

11:45 AM

Q&A and Closing Remarks

Participants will learn how Sim4Life enables image-based and regulatory-grade simulations featuring nerve and brain network models embedded within anatomically detailed representations of the human body. They will also discover how to create, execute, and automate computational pipelines in o²S²PARC to study realistic neuromodulation scenarios with a high degree of realism, ranging from network responses to non-invasive brain stimulation to the interactions between medical devices and the human body for bioelectronic medicine applications.

Attendees will directly interact with cloud-hosted pipelines that couple high-fidelity electromagnetic exposure modeling with neuronal dynamics – all in the browser, no local installations required.

Seats are limited, so register today!

 

Scientific Research

The IT'IS research team will also present six posters that describe their latest progress at the leading-edge of in silico neuroscience:

Poster No 039
Sunday, July 6, 2025, 17:20 CEST
In Silico Safety and Performance Assessment of Vagus Nerve Stimulation with Metamodeling-Based Uncertainty/Variability Quantification
Antonino Cassarà, Javier Garcia Ordonez, Werner Van Geit, and Esra Neufeld

Poster No 040
Sunday, July 6, 2025, 17:20 CEST
Modeling Transcranial Magnetic Stimulation: From Exposure in Personalized Head Models to Single Cell and Brain Network Dynamics Responses
Antonino Cassarà, Micol Colella, Esra Neufeld, Serena Santanche, Chiara Billi, and Micaela Liberti

Poster No 131
Monday, July 7, 2025, 16:20 CEST
Personalized Computational Models for Effective Impact-Driven Brain Stimulation
Fariba Karimi, Taylor Newton, Melanie Steiner, Antonino Cassara, Niels Kuster, and Esra Neufeld

Poster No 215
Monday, July 7, 2025, 16:20 CEST
Superior Temporal Interference Stimulation Targeting using Surrogate-based Multi-Goal Optimization
Esra Neufeld, Cedric Bujard, Melanie Steiner, and Niels Kuster (presented by Fariba Karimi)

Poster No 217
Monday, July 7, 2025, 16:20 CEST
The Generalized Activating Function: Accelerating Axonal Modeling for Optimized Neuromodulation
Javier García Ordóñez, Taylor Newton, Abdallah Alashqar, Andreas Rowald, Esra Neufeld, and Niels Kuster

Poster No 299
Tuesday, July 8, 2025, 17:00 CEST
iCSD May Produce Spurious Results in Dense Electrode Arrays
Joseph Tharayil, Esra Neufeld, Michael Reimann

For more information, see the event schedule CNS*2025 Program.

 

Why Meet Us in Florence?

  • Cloud-native workflows: Build, share and reproduce complex pipelines from magnetic resonance imaging to neuronal dynamics in minutes
  • Regulatory-grade in silico evidence: Validate neuromodulation devices with uncertainty-quantified EM, thermal and neuronal dynamics simulations
  • AI-accelerated design: Surrogate-accelerated tools slash exploration time from weeks to minutes

We look forward to exchanging ideas, forging collaborations, and enjoying some gelato together – see you in Florence! Ci vediamo a Firenze!

Corporate

May 30, 2025

Contact
info@zmt.swiss

 

 
Sim4Life

May 16, 2025

Contact
info@zmt.swiss

 

Sim4Life User Workshop and ZMT Exhibition at ISMRM 2025 in Honolulu

ISMRM 2025 was a big hit! Attendance was strong for the invited talks at the Sim4Life User Workshop and lunchtime Booth Talk series, which covered a wide range of exciting applications for Sim4life. ZMT also presented improvements to Sim4Life.web and the novel Low-Field Implant Safety Test Suite at the booth. More coming at the ISMRM Safety Workshop this autumn in Berlin!

 
Validation HW

May 6, 2025

Contact
info@zmt.swiss

 

 
Sim4Life

Apr 15, 2025

Contact
info@zmt.swiss

 

 
Sim4Life

Apr 14, 2025

Contact
info@zmt.swiss

 

Sim4Life V8.2.2 Maintenance Release

The Sim4Life Team announced the release of Sim4Life V8.2.2, an updated version of Sim4Life V8.2.0.

 
Sim4Life

Mar 11, 2025

Contact
info@zmt.swiss

 

Sim4Life.Web V8.4: The Prep Step for the Next Key Milestones – Sim4Life V9.0

With the launch of Sim4Life.web V8.4 – available exclusively on the sim4life.swiss web platform – we introduce “The Shop”, which includes all Virtual Population and electromagnetic anthropomorphic models. This release also introduces new functionalities that enhance your workflow and set the stage for the next major release – Sim4Life 9.0.

 
Corporate

Mar 3, 2025

Contact
info@zmt.swiss

 

Z43 Alliance Makes Strong Impact at Brain Stimulation 2025 in Kobe

In late February, ZMT and its Z43 partners participated in the 6th Brain Stimulation Conference in Kobe, Japan, with full days of insightful discussions, valuable engagement, and knowledge exchange.

 
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